Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| THCA | rs17397112 | chr3:139262623 | T/A | 4.49E-6 | 489 | 15.9 | 16.93 | 14.53 | KM Plot |
| THCA | rs1739827 | chr1:16326344 | C/T | 1.2E-11 | 488 | 15.23 | 18.28 | 12.63 | KM Plot |
| THCA | rs1739829 | chr1:16327967 | G/T | 1.14E-11 | 489 | 15.17 | 18.63 | 12.63 | KM Plot |
| THCA | rs1739839 | chr1:16341525 | G/A | 1.34E-11 | 487 | 15.17 | 18.63 | 12.63 | KM Plot |
| THCA | rs1739845 | chr1:16343815 | C/A | 1.62E-11 | 486 | 15.17 | 17.93 | 12.63 | KM Plot |
| THCA | rs1740610 | chr1:41502680 | C/A | 3.73E-12 | 489 | 17.7 | 17.73 | 14.92 | KM Plot |
| THCA | rs1740615 | chr1:41538516 | C/T | 4.54E-12 | 487 | 17.7 | 17.73 | 14.93 | KM Plot |
| THCA | rs17407513 | chr5:96231578 | A/C | 3.27E-6 | 489 | 15.83 | 16.92 | 17.7 | KM Plot |
| THCA | rs17407871 | chr5:96235593 | T/G | 3.27E-6 | 489 | 15.83 | 16.92 | 17.7 | KM Plot |
| THCA | rs17412043 | chr2:38225019 | G/T | 4.62E-9 | 490 | 16.6 | 14.1 | 11.73 | KM Plot |
| THCA | rs17470053 | chr10:70618422 | C/A | 1.37E-7 | 470 | 15.9 | 15 | 17.2 | KM Plot |
| THCA | rs17484348 | chr1:37065201 | A/G | 3.0E-15 | 490 | 7.07 | 16.93 | 15.7 | KM Plot |
| THCA | rs17486775 | chr5:96242400 | T/C | 3.27E-6 | 489 | 15.83 | 16.92 | 17.7 | KM Plot |
| THCA | rs17487132 | chr5:96248254 | T/G | 3.27E-6 | 489 | 15.83 | 16.92 | 17.7 | KM Plot |
| THCA | rs17492213 | chr12:58410685 | C/T | 7.96E-8 | 490 | 13.83 | 19 | 15.3 | KM Plot |